Description
PKG Substrate Glasstide
| Catalog number: | B2011347 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 mg |
| Molecular Weight or Concentration: | 902.1 g/mol |
| Supplied as: | Lyophilized |
| Applications: | molecular tool for various biochemical applications |
| Storage: | -20 C |
| Keywords: | protein kinase G susbtrate |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Plano SA, Alessandro MS, Trebucq LL, Endo S, Golombek DA, Chiesa JJ. Role of G-Substrate in the NO/cGMP/PKG Signal Transduction Pathway for Photic Entrainment of the Hamster Circadian Clock ASN Neuro. 2021 Jan-Dec;13:1759091420984920.
- Endo S. G-substrate: the cerebellum and beyond Prog Mol Biol Transl Sci. 2012;106:381-416.
- Schlossmann J, Desch M. IRAG and novel PKG targeting in the cardiovascular system Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H672-82.
- Morone PJ, Yan W, Adcock J, Komalavilas P, Mocco J, Thompson RC, Brophy C, Cheung-Flynn J. Vasorelaxing cell permeant phosphopeptide mimetics for subarachnoid hemorrhage Eur J Pharmacol. 2021 Jun 5;900:174038.
- Smolenski A. Novel roles of cAMP/cGMP-dependent signaling in platelets J Thromb Haemost. 2012 Feb;10(2):167-76.
- Alverdi V, Mazon H, Versluis C, Hemrika W, Esposito G, van den Heuvel R, Scholten A, Heck AJ. cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain J Mol Biol. 2008 Feb 1;375(5):1380-93.
- Nakazawa T, Endo S, Shimura M, Kondo M, Ueno S, Tamai M. Retinal G-substrate, potential downstream component of NO/cGMP/PKG pathway, is located in subtype of retinal ganglion cells and amacrine cells with protein phosphatases Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):58-68.
- Li L, Li L, Chen C, Yang J, Li J, Hu N, Li Y, Zhang D, Guo T, Liu X, Yang W. Scutellarins Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-I PLoS One. 2015 Oct 6;10(10):e0139570.
- Kim C, Sharma R. Cyclic nucleotide selectivity of protein kinase G isozymes Protein Sci. 2021 Feb;30(2):316-327.









