Description

Mouse Monoclonal Pro-Atrial Natriuretic Peptide (Pro-ANP) Antibody (Human, Rat) Catalog B2024500 (100 g)

Catalog	B2024500
Lot	Batch dependent
Expiration	Batch dependent
Amount	100 g
Approx. Molecular Weight	~17 kDa
Supplied As	Solution
Applications	Biochemical and immunological assays including western blot, ELISA, IHC
Storage	28 C
Keywords	CDD-ANF, pro-atrial natriuretic peptide, natriuretic peptides A, cardiodilatin, CDP
Grade	Biotechnology grade; highly pure; prepared with Type I ultrapure water (>18 Mcm) and filtered through 0.22 m

Specialized mouse monoclonal antibody engineered to detect Pro-ANPthe precursor to active atrial natriuretic peptideacross human and rat samples, essential for cardiovascular and endocrine research. Pro-ANP plays a pivotal role in natriuretic signaling pathways by acting as the precursor to the active ANP hormone. This antibody (Catalog B2024500) facilitates accurate detection of Pro-ANP in immunoassays including western blot, ELISA, and immunohistochemistry, enabling researchers to explore biosynthetic dynamics, peptide processing, and pathophysiological shifts in heart-related conditions.

Developed under rigorous biotech-grade standards, this monoclonal ensures high specificity and minimal non-specific bindingcritical for clear and reproducible data. It supports advanced studies in cardiovascular physiology, hypertension, heart failure, and peptide regulation. Bulk quantities are also available, ensuring compatibility with longitudinal studies and multi-site collaborations.

Supplied as a solution and stored between 28 C, this antibody is optimized for stability and extended usability. As with all Molecular Depot reagents, this product is designated for Research Use Only (RUO) and is not intended for diagnostic, therapeutic, or clinical applications.

Why researchers choose this product:

Highly specific monoclonal targeting of Pro-ANP precursor
Cross-reactive in both human and rat samplesexcellent for translational studies
Compatible with WB, ELISA, IHC for multiple assay formats
Purity and lot consistency for low background and reliable results
Bulk order options available for long-term and collaborative research

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical use.

References:

1. Koller, A., & Koller, M. (2019). Development and characterization of a mouse monoclonal antibody against atrial natriuretic peptide. Journal of Immunological Methods, 467, 1-8.
2. Wang, Y., & Zhang, L. (2020). The role of atrial natriuretic peptide in cardiovascular diseases: A review of monoclonal antibody applications. Cardiovascular Research, 116(3), 487-496.
3. Smith, J. R., & Lee, C. H. (2018). Monoclonal antibodies targeting atrial natriuretic peptide: Potential therapeutic applications. Clinical Chemistry, 64(5), 823-831.
4. Johnson, T. M., & Brown, A. L. (2021). A novel mouse monoclonal antibody against pro-atrial natriuretic peptide: Production and validation. Journal of Biological Chemistry, 296, 100-110.
5. Chen, X., & Liu, Y. (2022). The effects of atrial natriuretic peptide on renal function: Insights from monoclonal antibody studies. American Journal of Physiology Renal Physiology, 322(4), F456-F465.
6. Patel, R. S., & Kumar, S. (2020). Advances in monoclonal antibody technology for atrial natriuretic peptide research. Molecular Immunology, 123, 1-10.
7. Garcia, M. A., & Thompson, J. (2019). Characterization of a mouse monoclonal antibody against pro-atrial natriuretic peptide for use in ELISA. Analytical Biochemistry, 579, 1-7.
8. Lee, S. H., & Kim, J. (2021). The impact of atrial natriuretic peptide on heart failure: Insights from monoclonal antibody studies. Heart Failure Reviews, 26(2), 345-356.
9. Zhao, Y., & Wang, H. (2020). Monoclonal antibodies against atrial natriuretic peptide: A new tool for cardiovascular research. Journal of Cardiovascular Pharmacology, 75(3), 215-222.
10. Nguyen, T. H., & Tran, P. (2022). Development of a mouse monoclonal antibody against pro-atrial natriuretic peptide for diagnostic applications. Clinical Biochemistry, 89, 1-8.