Description
Sphingosine kinase 2 Active Human
| Catalog number: | B2019699 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 10 ug |
| Molecular Weight or Concentration: | 69.5 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 70C |
| Keywords: | SK2, SPHK2, SPK 2 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Yokoyama S, Koo I, Aibara D, Tian Y, Murray IA, Collins SL, Coslo DM, Kono M, Peters JM, Proia RL, Gonzalez FJ, Perdew GH, Patterson AD. Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation Adv Sci (Weinh). 2024 Oct;11(40):e2400794.
- Hamdan N, Bhagirath AY, Batista EL Jr. Sphingosine kinase activity and sphingosine-1-phosphate in the inflamed human periodontium Oral Dis. 2023 Jan;29(1):265-273.
- Weigel C, Maczis MA, Palladino END, Green CD, Maceyka M, Guo C, Wang XY, Dozmorov MG, Milstien S, Spiegel S. Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer Cancer Res. 2023 Feb 15;83(4):553-567.
- Mu Y, Wang J, Li G. Sphingosine kinase-2 silencing modulates sensitivity of HT-29 human colorectal cancer cells to paclitaxel-induced cell death through altering apoptosis-related proteins Chem Biol Drug Des. 2023 Aug;102(2):255-261.
- Pyne NJ, El Buri A, Adams DR, Pyne S. Sphingosine 1-phosphate and cancer Adv Biol Regul. 2018 May;68:97-106.
- Rohrbach T, Maceyka M, Spiegel S. Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology Crit Rev Biochem Mol Biol. 2017 Oct;52(5):543-553.
- Ding X, Zhang X, Cao J, Chen S, Chen Y, Yuan K, Chen B, Yang G, Li S, Yang J, Wang G, Tacke F, Lan T. Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and Polarization Cell Mol Gastroenterol Hepatol. 2024;18(6):101406.
- Aji G, Jiang S, Obulkasim H, Lu Z, Wang W, Xia P. Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes Exp Biol Med (Maywood). 2023 Jan;248(1):44-51.
- Zhou J, Chen J, Yu H. Targeting sphingosine kinase 2 by ABC294640 inhibits human skin squamous cell carcinoma cell growth Biochem Biophys Res Commun. 2018 Mar 4;497(2):535-542.
