Description
CD4 Chimeric Monoclonal Antibody
| Catalog number: | B2017715 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 100 g |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | SOLUTION |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | Cluster of Differentiation 4, T Cell Surface Antigen T4, T Cell Surface Glycoprotein CD4 |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Moreland LW, Pratt PW, Sanders ME, Koopman WJ. Experience with a chimeric monoclonal anti-CD4 antibody in the treatment of refractory rheumatoid arthritis Clin Exp Rheumatol. 1993 Mar-Apr;11 Suppl 8:S153-9.
- Moreland LW, Pratt PW, Bucy RP, Jackson BS, Feldman JW, Koopman WJ. Treatment of refractory rheumatoid arthritis with a chimeric anti-CD4 monoclonal antibody. Long-term followup of CD4+ T cell counts Arthritis Rheum. 1994 Jun;37(6):834-8.
- Edwards JM, Heydarchi B, Khoury G, Salazar-Quiroz NA, Gonelli CA, Wines B, Hogarth PM, Kristensen AB, Parsons MS, Purcell DFJ. Enhancement of Antibody-Dependent Cellular Cytotoxicity and Phagocytosis in Anti-HIV-1 Human-Bovine Chimeric Broadly Neutralizing Antibodies J Virol. 2021 Jun 10;95(13):e0021921.
- van Oosten BW, Lai M, Hodgkinson S, Barkhof F, Miller DH, Moseley IF, Thompson AJ, Rudge P, McDougall A, McLeod JG, Adr HJ, Polman CH. Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial Neurology. 1997 Aug;49(2):351-7.
- Looney JE, Willinger A, Lin G, Rieber EP, Riethmuller G, Ghrayeb J. Expression and characterization of cM-T413, a chimeric anti-CD4 antibody with in vitro immunosuppressive activity J Immunother Emphasis Tumor Immunol. 1994 Jul;16(1):36-46.
- Moreland LW, Pratt PW, Mayes MD, Postlethwaite A, Weisman MH, Schnitzer T, Lightfoot R, Calabrese L, Zelinger DJ, Woody JN, et al. Double-blind, placebo-controlled multicenter trial using chimeric monoclonal anti-CD4 antibody, cM-T412, in rheumatoid arthritis patients receiving concomitant methotrexate Arthritis Rheum. 1995 Nov;38(11):1581-8.
- Lan X, Yang TTC, Wang Y, Qu B, Rong S, Song N. Characterization of 405B8H3(D-E), a newly engineered high affinity chimeric LAG-3 antibody with potent antitumor activity FEBS Open Bio. 2023 Jul;13(7):1253-1265.
- Taylor PC. Antibody therapy for rheumatoid arthritis Curr Opin Pharmacol. 2003 Jun;3(3):323-8.
- Choy EH, Schantz A, Pitzalis C, Kingsley GH, Panayi GS. The pharmacokinetics and human anti-mouse antibody response in rheumatoid arthritis patients treated with a chimeric anti-CD4_monoclonal antibody Br J Rheumatol. 1998 Jul;37(7):801-2.
