Description
Corn Trypsin Inhibitor (CTI)
| Catalog number: | B2016600 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 500 ug |
| Molecular Weight or Concentration: | 12500 |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | 80C |
| Keywords: | Corn Trypsin Inhibitor (CTI) |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Alibeik S, Zhu S, Yau JW, Weitz JI, Brash JL. Dual surface modification with PEG and corn trypsin inhibitor: effect of PEG:CTI ratio on protein resistance and anticoagulant properties J Biomed Mater Res A. 2012 Apr;100(4):856-62.
- Hansson KM, Nielsen S, Elg M, Deinum J. The effect of corn trypsin inhibitor and inhibiting antibodies for FXIa and FXIIa on coagulation of plasma and whole blood J Thromb Haemost. 2014 Oct;12(10):1678-86.
- Touw CE, de Jong Y, van Hylckama Vlieg A. The influence of corn trypsin inhibitor on the contribution of coagulation determinants to the Technoclone Thrombin Generation Assay (TGA) and the Calibrated Automated Thrombogram (CAT) PLoS One. 2022 Feb 25;17(2):e0263960.
- Hamad BK, Pathak M, Manna R, Fischer PM, Emsley J, Dekker LV. Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation J Thromb Haemost. 2017 Sep;15(9):1818-1828.
- van Veen JJ, Gatt A, Cooper PC, Kitchen S, Bowyer AE, Makris M. Corn trypsin inhibitor in fluorogenic thrombin-generation measurements is only necessary at low tissue factor concentrations and influences the relationship between factor VIII coagulant activity and thrombogram parameters Blood Coagul Fibrinolysis. 2008 Apr;19(3):183-9.
- Yau JW, Stafford AR, Liao P, Fredenburgh JC, Roberts R, Brash JL, Weitz JI. Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo Acta Biomater. 2012 Nov;8(11):4092-100.
- Nielsen VG. Corn trypsin inhibitor decreases tissue-type plasminogen activator-mediated fibrinolysis of human plasma Blood Coagul Fibrinolysis. 2009 Apr;20(3):191-6.
- Zhu S, Herbig BA, Yu X, Chen J, Diamond SL. Contact Pathway Function During Human Whole Blood Clotting on Procoagulant Surfaces Front Med (Lausanne). 2018 Jul 23;5:209.
- Alibeik S, Zhu S, Yau JW, Weitz JI, Brash JL. Modification of polyurethane with polyethylene glycol-corn trypsin inhibitor for inhibition of factor Xlla in blood contact J Biomater Sci Polym Ed. 2012;23(15):1981-93.
