Description
Glutaminase
| Catalog number: | B2020190 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 1 kU |
| Molecular Weight or Concentration: | 58 kDa |
| Supplied as: | Lyophilized |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | L-Glutamine amidohydrolase |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
- Ji C, Tang Y, Zhang Y, Li C, Liang H, Ding L, Xia X, Xiong L, Qi XR, Zheng JC. Microglial glutaminase 1 deficiency mitigates neuroinflammation associated depression Brain Behav Immun. 2022 Jan;99:231-245.
- Masisi BK, El Ansari R, Alfarsi L, Rakha EA, Green AR, Craze ML. The role of glutaminase in cancer Histopathology. 2020 Mar;76(4):498-508.
- Wu C, Chen L, Jin S, Li H. Glutaminase inhibitors: a patent review Expert Opin Ther Pat. 2018 Nov;28(11):823-835.
- Ding L, Xu X, Li C, Wang Y, Xia X, Zheng JC. Glutaminase in microglia: A novel regulator of neuroinflammation Brain Behav Immun. 2021 Feb;92:139-156.
- Dumontet C. Targeting glutaminase to starve lymphoma cells Haematologica. 2023 Jun 1;108(6):1468-1469.
- Cyriac R, Lee K. Glutaminase inhibition as potential cancer therapeutics: current status and future applications J Enzyme Inhib Med Chem. 2024 Dec;39(1):2290911.
- Chen Y, Tan L, Gao J, Lin C, Wu F, Li Y, Zhang J. Targeting glutaminase 1 (GLS1) by small molecules for anticancer therapeutics Eur J Med Chem. 2023 Apr 5;252:115306.
- Ji C, Tang Y, Zhang Y, Huang X, Li C, Yang Y, Wu Q, Xia X, Cai Q, Qi XR, Zheng JC. Glutaminase 1 deficiency confined in forebrain neurons causes autism spectrum disorder-like behaviors Cell Rep. 2023 Jul 25;42(7):112712.
- Adamoski D, M Dos Reis L, Mafra ACP, Corra-da-Silva F, Moraes-Vieira PMM, Berindan-Neagoe I, Calin GA, Dias SMG. HuR controls glutaminase RNA metabolism Nat Commun. 2024 Jul 4;15(1):5620.
