Description
Human Citrullinated Histone H4
| Catalog number: | B2016730 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 13.4 kDa |
| Supplied as: | Solution |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -80C |
| Keywords: | Citrullinated Histone H4 (human, recombinant; His-tagged) |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- Andrs M, Garca-Gomis D, Ponte I, Suau P, Roque A. Histone H1 Post-Translational Modifications: Update and Future Perspectives Int J Mol Sci. 2020 Aug 18;21(16):5941.
- Tessarz P, Kouzarides T. Histone core modifications regulating nucleosome structure and dynamics Nat Rev Mol Cell Biol. 2014 Nov;15(11):703-8.
- Tian Y, Li P, Wu Z, Deng Q, Pan B, Stringer KA, Alam HB, Standiford TJ, Li Y. Citrullinated Histone H3 Mediates Sepsis-Induced Lung Injury Through Activating Caspase-1 Dependent Inflammasome Pathway Front Immunol. 2021 Dec 7;12:761345.
- Zuo Y, Yalavarthi S, Shi H, Gockman K, Zuo M, Madison JA, Blair C, Weber A, Barnes BJ, Egeblad M, Woods RJ, Kanthi Y, Knight JS. Neutrophil extracellular traps in COVID-19 JCI Insight. 2020 Jun 4;5(11):e138999.
- Shi L, Aymonnier K, Wagner DD. Neutrophil stimulation with citrullinated histone H4 slows down calcium influx and reduces NET formation compared with native histone H4 PLoS One. 2021 May 17;16(5):e0251726.
- Masuda S, Nakazawa D, Shida H, Miyoshi A, Kusunoki Y, Tomaru U, Ishizu A. NETosis markers: Quest for specific, objective, and quantitative markers Clin Chim Acta. 2016 Aug 1;459:89-93.
- Wong SL, Demers M, Martinod K, Gallant M, Wang Y, Goldfine AB, Kahn CR, Wagner DD. Diabetes primes neutrophils to undergo NETosis, which impairs wound healing Nat Med. 2015 Jul;21(7):815-9.
- Perdomo J, Leung HHL, Ahmadi Z, Yan F, Chong JJH, Passam FH, Chong BH. Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia Nat Commun. 2019 Mar 21;10(1):1322.
