Description
Human MEK2 Protein Inactive
| Catalog number: | B2014001 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 50 g |
| Molecular Weight or Concentration: | 46 kDa |
| Supplied as: | N/A |
| Applications: | molecular tool for various biochemical applications |
| Storage: | 20C |
| Keywords: | MEK2 Protein |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
References
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- Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes Nature. 2019 Nov;575(7783):545-550.
- Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R; Cancer Genome Project. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF Cell. 2004 Mar 19;116(6):855-67.
- Reiterer V, Pawowski K, Farhan H. STYX: a versatile pseudophosphatase Biochem Soc Trans. 2017 Apr 15;45(2):449-456.
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- Brott BK, Alessandrini A, Largaespada DA, Copeland NG, Jenkins NA, Crews CM, Erikson RL. MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues Cell Growth Differ. 1993 Nov;4(11):921-9.
- Hsiao KM, Chou SY, Shih SJ, Ferrell JE Jr. Evidence that inactive p42 mitogen-activated protein kinase and inactive Rsk exist as a heterodimer in vivo Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5480-4.
- Pouyssgur J, Volmat V, Lenormand P. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling Biochem Pharmacol. 2002 Sep;64(5-6):755-63.
- Wang W, Krosky D, Ahn K. Discovery of Inactive Conformation-Selective Kinase Inhibitors by Utilizing Cascade Assays Biochemistry. 2017 Aug 29;56(34):4449-4456.
