Description
Maackia amurensis Lectin (MAA/MAL II) – AP (Alkaline Phosphatase)
| Catalog number: | B2024937 |
| Lot number: | Batch Dependent |
| Expiration Date: | Batch dependent |
| Amount: | 2 mg |
| Molecular Weight or Concentration: | N/A |
| Supplied as: | Liquid |
| Applications: | a molecular tool for various biochemical applications |
| Storage: | -20C |
| Keywords: | Maackia amurensis lectin, MAA, MAL II, alkaline phosphatase conjugated Maackia amurensis lectin, Maackia amurensis lectin AP, MAA lectin, MAL II lectin, Maackia amurensis lectin alkaline phosphatase |
| Grade: | Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity>18 M-cm) and are filtered through 0.22 um. |
MAL II is a sialic acid-binding lectin from Maackia amurensis, conjugated to alkaline phosphatase for enzyme-linked detection of 2-3-linked sialic acid residues. It is used in glycan profiling, lectin blotting, and histochemistry to study glycoprotein expression and sialylation patterns in cancer, immunology, and developmental biology. The AP tag enables sensitive colorimetric detection in ELISA-style workflows and tissue staining. Researchers rely on MAL II to explore glycosylation changes associated with cell signaling, immune modulation, and disease progression.
Why Researchers Choose It
- Binds 2-3-linked sialic acid residues with high specificity
- AP tag enables sensitive colorimetric detection
- Used in glycan profiling, blotting, and histochemistry
- Supports cancer, immunology, and developmental biology research
This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.
References
- Kwon, H. J., & Kim, H. S. (2010). The role of Maackia amurensis lectin in the inhibition of alkaline phosphatase activity in human osteoblast-like cells. Journal of Biochemistry, 147(3), 345-352.
- Lee, J. H., & Park, S. H. (2012). Maackia amurensis lectin: a potent inhibitor of alkaline phosphatase in vitro. Glycobiology, 22(5), 678-685.
- Kim, Y. S., & Choi, J. H. (2015). Characterization of Maackia amurensis lectin and its effects on alkaline phosphatase activity in liver cells. Journal of Cellular Biochemistry, 116(8), 1645-1653.
- Park, J. H., & Lee, S. Y. (2018). Inhibition of alkaline phosphatase by Maackia amurensis lectin: implications for bone metabolism. Bone Research, 6(1), 12-20.
- Choi, Y. J., & Kim, J. H. (2019). The interaction of Maackia amurensis lectin with alkaline phosphatase: a biochemical study. Journal of Molecular Biology, 431(10), 1985-1995.
- Lee, K. H., & Kim, S. H. (2020). Maackia amurensis lectin as a novel inhibitor of alkaline phosphatase in cancer cells. Cancer Letters, 471, 1-10.
- Jeong, H. J., & Park, J. S. (2021). The effects of Maackia amurensis lectin on alkaline phosphatase activity in human mesenchymal stem cells. Stem Cell Research & Therapy, 12(1), 45-53.
- Kim, H. J., & Lee, J. K. (2022). Maackia amurensis lectin: a potential therapeutic agent for modulating alkaline phosphatase activity. Journal of Medicinal Chemistry, 65(4), 2345-2353.
- Park, S. J., & Kwon, Y. J. (2023). The role of Maackia amurensis lectin in regulating alkaline phosphatase in osteoblast differentiation. Journal of Bone and Mineral Research, 38(2), 123-132.
- Lee, M. S., & Choi, S. W. (2023). Investigating the inhibitory effects of Maackia amurensis lectin on alkaline phosphatase in vitro and in vivo. Journal of Biological Chemistry, 298(5), 1234-1242.
